Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622135 | 0.62 | — | — | |
| SCHEMBL29275518 | 0.60 | DNTT (0.37) | DNTTPOLBPOLA1ALDH1A1 | |
| SCHEMBL16066298 | 0.58 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL5693612 | 0.58 | — | — | |
| SCHEMBL718211 | 0.57 | — | — | |
| SCHEMBL31534656 | 0.56 | DNTT (0.51) | DNTTPOLBPOLA1ALDH1A1 | |
| SCHEMBL16498749 | 0.54 | — | — | |
| SCHEMBL6752183 | 0.54 | MEN1 (0.30) | — | |
| SCHEMBL11133104 | 0.53 | GAA (0.36) | ALDH1A1 | |
| SCHEMBL8646012 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890993-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR ANTAGONISTS OF GLYR | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006121390-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR AGONISTS OF GLYR | ASTRAZENECA AB (SE) | 2006-11-16 | — | — | WO | disclosed |