Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646451 | 0.85 | MAPT (0.47) | MAPTTACR1GPR119RORCMMP13 | |
| SCHEMBL3247703 | 0.78 | USP2 (0.47) | MAPTTACR1GPR119RORCALOX15 | |
| SCHEMBL6795066 | 0.78 | MAPT (0.55) | MAPTTACR1GPR119RORCSTS | |
| SCHEMBL13131400 | 0.76 | GPR119 (0.54) | MAPTTACR1GPR119TSHR | |
| SCHEMBL4244426 | 0.76 | MAPT (0.53) | MAPTTACR1GPR119RORCP2RY14 | |
| SCHEMBL30835990 | 0.75 | MAPT (0.50) | MAPTTACR1GPR119RORCP2RY14 | |
| SCHEMBL645190 | 0.75 | MAPT (0.47) | MAPTTACR1GPR119RORCSTS | |
| SCHEMBL24484249 | 0.75 | MAPT (0.52) | MAPTTACR1GPR119RORCSTS | |
| SCHEMBL24485515 | 0.74 | MAPT (0.51) | MAPTTACR1GPR119RORCSTS | |
| SCHEMBL30600319 | 0.74 | MAPT (0.51) | MAPTTACR1GPR119RORCP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |