Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463170 | 0.83 | MIF (0.46) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL11536892 | 0.79 | MIF (0.47) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL27730899 | 0.78 | MIF (0.46) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL472153 | 0.76 | MIF (0.41) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL11982130 | 0.76 | TDP1 (0.46) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL15747683 | 0.76 | MIF (0.45) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL9613490 | 0.76 | TDP1 (0.46) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL6966144 | 0.76 | MIF (0.45) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL15354918 | 0.76 | MIF (0.45) | MIFALDH1A1ALOX15MEN1MAPT | |
| SCHEMBL91215 | 0.76 | TDP1 (0.46) | MIFALDH1A1ALOX15MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | CERNOFINA, LLC | 2009-05-14 | — | — | US | disclosed |
| EP-1967520-A2 | Production of polyketides and other natural products | Biotica Technology Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| EP-1589031-B1 | Production of polyketides and other natural products | BIOTICA TECH LTD (GB) | 2007-08-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | SELP, SELE, SELPLG | MIF 144/4885ALDH1A1 1723/4885ALOX15 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.