Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.64 |
| ▸ | RAD52 | P43351 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NSD2 | O96028 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.59 |
| ▸ | PDE4A | P27815 | 6/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011364 | 0.94 | CYP2C9 (0.70) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5070029 | 0.88 | ADRB2 (0.77) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5011527 | 0.86 | PDE4B (0.76) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5014737 | 0.82 | ADRB2 (0.80) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5060130 | 0.80 | ADRB2 (0.75) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5011372 | 0.80 | PDE4B (0.89) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5012432 | 0.80 | PDE4B (0.70) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5011553 | 0.79 | ADRB2 (0.71) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5015884 | 0.79 | PDE4B (0.88) | ADRB2RAD52KMT2AL3MBTL1HTT | |
| SCHEMBL5014744 | 0.79 | PDE4B (0.88) | ADRB2RAD52KMT2AL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PAGES SANTACANA LUIS MIGUEL | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PDE4A, PDE5A, PDE3B | ADRB2 584/4885RAD52 2936/4885KMT2A 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.