Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11012667 | 0.91 | GAA (0.55) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL29043224 | 0.89 | KMT2A (0.58) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL30544799 | 0.89 | KMT2A (0.58) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL28315291 | 0.79 | ALDH1A1 (0.50) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL1900411 | 0.78 | MEN1 (0.46) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL11211849 | 0.78 | MEN1 (0.68) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL11342058 | 0.78 | BCL2 (0.58) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL8380031 | 0.78 | KDM4E (0.58) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL31255510 | 0.77 | KMT2A (0.53) | GAAMEN1USP2KMT2AKEAP1 | |
| SCHEMBL28126760 | 0.77 | HPGD (0.54) | GAAMEN1USP2KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105513-B2 | Pipette tip containing particle-filled polymer monolith | BONN ALEXANDER (AT) | 2012-01-31 | — | — | US | disclosed |
| US-20100009845-A1 | Pipette Tip Containing Particle-Filled Polymer Monolith | BONN ALEXANDER | 2010-01-14 | — | — | US | disclosed |