Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA5A | P35218 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810955 | 0.77 | MAPT (0.41) | CA2CA1CA9CA12S100A4 | |
| SCHEMBL5013818 | 0.75 | PTPN1 (0.46) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL196508 | 0.75 | BCL2 (0.38) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL811922 | 0.74 | TSHR (0.43) | CA2CA1CA9CA12HSD11B1 | |
| SCHEMBL197625 | 0.74 | TSHR (0.58) | TSHR | |
| SCHEMBL197299 | 0.72 | CA2 (0.40) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL197436 | 0.71 | TSHR (0.46) | CA2CA1CA9CA12TSHR | |
| SCHEMBL197679 | 0.70 | TDP1 (0.42) | CA2CA1CA9CA12HSD11B1 | |
| SCHEMBL5013838 | 0.70 | CA1 (0.32) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL197132 | 0.69 | TSHR (0.44) | CA2CA1CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127320-A2 | ARYLENE-FLUORINATED-SULFONIMIDE IONOMERS AND MEMBRANES FOR FUEL CELLS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-23 | — | — | WO | disclosed |