Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 8/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455451 | 0.81 | KDM4E (0.65) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL811455 | 0.78 | MAPT (0.80) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1454782 | 0.77 | MAPT (0.78) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17080167 | 0.74 | KDM4E (0.56) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1455467 | 0.74 | MAPT (0.72) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15227961 | 0.72 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18381544 | 0.72 | KDM4E (0.58) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6511279 | 0.70 | KDM4E (0.66) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1454579 | 0.70 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7360846 | 0.69 | KDM4E (0.64) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |