SCHEMBL6511279

SCHEMBL6511279

COC(=O)c1ccc(SSc2ccc(C(=O)OC)cc2N)c(N)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.66
MAPT P10636 9/20 0.66
ALDH1A1 P00352 8/20 0.66
HPGD P15428 7/20 0.66
HSD17B10 Q99714 4/20 0.66
LMNA P02545 3/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
ALOX15 P16050 2/20 0.66
MAPK1 P28482 2/20 0.66
NPSR1 Q6W5P4 2/20 0.64
GAA P10253 4/20 0.64
GLA P06280 1/20 0.64
CASP1 P29466 1/20 0.64
CASP7 P55210 1/20 0.64
ATM Q13315 1/20 0.64
USP2 O75604 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
MEN1 O00255 1/20 0.53
TP53 P04637 1/20 0.53
ALOX12 P18054 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7360846 0.88 KDM4E (0.64) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL27947356 0.86 KDM4E (0.62) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL19328513 0.86 KDM4E (0.59) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL24412 0.81 CA12 (0.69) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL29357340 0.81 CA12 (0.69) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL10954073 0.81 LMNA (0.57) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL8087032 0.81 KDM4E (0.57) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL8101784 0.81 KDM4E (0.57) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL18381840 0.81 KDM4E (0.67) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL192100 0.81 KDM4E (0.72) KDM4EMAPTALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066344-A1 BENZOTHIAZOLE, BENZOISOXAZOLE, AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-02-27 US disclosed
EP-4448500-A1 BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS Bristol-Myers Squibb Company (US) 2024-10-23 EP disclosed
WO-2023114822-A1 BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-06-22 WO disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066344-A1 BENZOTHIAZOLE, BENZOISOXAZOLE, AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS RXFP1, RXFP2, RXFP3 KDM4E 2968/4885MAPT 4598/4885ALDH1A1 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.