Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7362808 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1111714 | 0.93 | ALDH1A1 (0.61) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11152425 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13192566 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11159431 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL17261314 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8914849 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL376816 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL420011 | 0.85 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1931125 | 0.85 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436949-B | Tetradentate ligand, metal complex, and preparation methods and applications thereof | 上海巽田科技股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114436949-A | Tetradentate ligand and metal complex, and preparation method and application thereof | 上海巽田科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3102576-B1 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS INC (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2678349-B1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-9139609-B2 | C-4″ position substituted macrolide derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| EP-2678349-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-01 | — | — | EP | disclosed |
| CN-103492404-A | C-4' substituted macrolide derivatives | TAISHO PHARMACEUTICAL CO LTD | 2014-01-01 | — | — | CN | disclosed |
| WO-2012115256-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-30 | — | — | WO | disclosed |
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |
| EP-0464509-A1 | Biphosphonic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4933369-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0361482-A1 | Dimethyl tyrosyl amide sulfides, sulfoxides and sulfones | G.D. Searle & Co. (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |
| US-4415591-A | MIXTURE WITH A MONOAMINE OXIDASE | GEORGIA TECH RESEARCH INSTITUTE (US) | 1983-11-15 | — | — | US | disclosed |
| US-4308283-A | FUNGICIDES, BACTERICIDES | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4260634-A | PHENYLTHIOALKYLAMIDES, BACTERICIDES, FUNGICIDES | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4246201-A | Substituted N-(3-phenylthiopropyl)-3,3-diphenyl-propylamines possessing pharmacological activity | ALFA FARMACEUTICI, S.P.A. (IT) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MRPL21, MRPS34, MRPL37 | ALDH1A1 4667/4885MAPK1 2555/4885CYP1A2 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.