Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 12/20 | 0.97 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | XBP1 | P17861 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015555 | 0.92 | KCNH3 (1.00) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL5023687 | 0.86 | KCNH3 (0.84) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1391142 | 0.82 | MAPT (0.87) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL10243636 | 0.80 | MAPT (0.79) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1391167 | 0.78 | MAPT (0.81) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1391420 | 0.78 | MAPT (0.81) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1390857 | 0.78 | KCNH3 (0.65) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1923791 | 0.78 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL1390625 | 0.78 | MAPT (0.71) | KCNH3MAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1390912 | 0.78 | MAPT (0.71) | KCNH3MAPTMAPK1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |