Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062273 | 1.00 | KDM4E (0.36) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2310267 | 0.94 | ALDH1A1 (0.34) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2307642 | 0.94 | LRRK2 (0.34) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5014410 | 0.94 | ALDH1A1 (0.34) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2310416 | 0.92 | MAPK1 (0.38) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5011019 | 0.92 | ALDH1A1 (0.35) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2309986 | 0.92 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2308649 | 0.91 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2308126 | 0.91 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2305806 | 0.91 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |