Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195637 | 1.00 | CA2 (0.42) | CA2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL15209687 | 1.00 | CA2 (0.42) | CA2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL2679184 | 0.94 | CA2 (0.39) | CA2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL7666492 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 | |
| SCHEMBL16702733 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 | |
| SCHEMBL23498813 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 | |
| SCHEMBL10519624 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 | |
| SCHEMBL7767174 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 | |
| SCHEMBL3307047 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 | |
| SCHEMBL7511263 | 0.91 | CA2 (0.48) | CA2FFAR4FFAR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312112-A1 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction | LYON DEVELOPMENT CORPORATION | 2008-12-18 | — | — | US | disclosed |