Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL5016656 | 0.89 | BBOX1 (0.31) | BBOX1 | |
| Lithium Ion SCHEMBL5014784 | 0.86 | BBOX1 (0.34) | BBOX1GMNNALDH1A1LMNATP53 | |
| Lithium Ion SCHEMBL5014309 | 0.83 | BBOX1 (0.37) | BBOX1GMNNALDH1A1LMNATP53 | |
| Lithium Ion SCHEMBL5014274 | 0.82 | BBOX1 (0.39) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL5014788 | 0.78 | APP (0.34) | — | |
| Lithium Ion SCHEMBL5016660 | 0.76 | BBOX1 (0.34) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL2058002 | 0.76 | — | — | |
| Lithium Ion SCHEMBL5016644 | 0.76 | BBOX1 (0.36) | BBOX1GMNNALDH1A1LMNATP53 | |
| Lithium Ion SCHEMBL5022481 | 0.74 | — | — | |
| SCHEMBL2058111 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9118062-B2 | Anode and method of manufacturing the same, and battery and method of manufacturing the same | SONY CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20080311472-A1 | ANODE AND METHOD OF MANUFACTURING THE SAME, AND BATTERY AND METHOD OF MANUFACTURING THE SAME | SONY CORPORATION (JP) | 2008-12-18 | — | — | US | disclosed |