Dichlorodifluoromethane

Dichlorodifluoromethane

SCHEMBL5014895

FC(F)(Cl)Cl.FC(F)(F)C(F)(Cl)Cl

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866 0.94
Trichloromonofluoromethane SCHEMBL4620269 0.89 ALDH1A1 (0.30) ALDH1A1LMNACYP2E1TSHR
Fluoride SCHEMBL27295812 0.89
Charcoal, Activated SCHEMBL30130135 0.89
SCHEMBL4805407 0.84
Fluoromethane SCHEMBL9059376 0.84 TSHR (0.33) TSHR
Dichlorotetrafluoroethane SCHEMBL22832126 0.84
Chloropentafluoroethane SCHEMBL11557068 0.84
Dichlorodifluoromethane SCHEMBL485 0.82
Dichlorodifluoromethane SCHEMBL10828892 0.82 TSHR (0.43) ALDH1A1LMNACYP2E1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066016-B2 POLY-AMINOACID DERIVATIVES AND THEIR USE IN COMPOSITIONS FOR TREATING KERATINOUS FIBRES OREAL (FR) 2008-09-24 EP disclosed
EP-1705187-A1 Cosmetic compositions comprising KAP-polypeptides for care, strengthening, and/or repair of substrates consisting of keratin L'OREAL (FR) 2006-09-27 EP disclosed
EP-1066016-B1 POLY-AMINOACID DERIVATIVES AND THEIR USE IN COMPOSITIONS FOR TREATING KERATINOUS FIBRES OREAL (FR) 2005-07-06 EP disclosed
EP-1066016-A1 POLY-AMINOACID DERIVATIVES AND THEIR USE IN COMPOSITIONS FOR TREATING KERATINOUS FIBRES L'OREAL (FR) 2001-01-10 EP disclosed
WO-1999049837-A1 POLY-AMINOACID DERIVATIVES AND THEIR USE IN COMPOSITIONS FOR TREATING KERATINOUS FIBRES L'OREAL (FR) 1999-10-07 WO disclosed
EP-0478456-B1 Antifungal composition in dry aerosol form OREAL (FR) 1995-01-18 EP disclosed
EP-0485299-B1 Aerosol foam anhydrous cosmetic composition OREAL (FR) 1994-09-14 EP disclosed
EP-0485299-A1 Aerosol foam anhydrous cosmetic composition L'OREAL (FR) 1992-05-13 EP disclosed
US-4062937-A ALKALI METAL GLUTAMATE REA LA VERNE 1977-12-13 US disclosed
US-4010252-A POLYQUATERNARY AMMONIUM COMPOUND, DEODORANTS COLGATE-PALMOLIVE COMPANY (US) 1977-03-01 US disclosed