Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4856303 | 0.99 | LGMN (0.41) | LGMNALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4858569 | 0.91 | LGMN (0.39) | LGMNALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL18092165 | 0.91 | TMEM97 (0.35) | LGMNALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6021719 | 0.91 | LGMN (0.39) | LGMNALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4851451 | 0.91 | LGMN (0.39) | LGMNALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4852055 | 0.90 | TMEM97 (0.35) | LGMNALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4858389 | 0.90 | LGMN (0.38) | LGMNALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4853414 | 0.89 | MAPT (0.35) | LGMNALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4856861 | 0.89 | LGMN (0.38) | LGMNALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL5016684 | 0.88 | LGMN (0.39) | LGMNALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410971-B2 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | CCR10, HRH3, HRH1 | LGMN 4885/4885ALDH1A1 707/4885KMT2A 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.