Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545799 | 0.81 | ADORA2A (0.64) | ADORA2AADORA2BADORA1 | |
| SCHEMBL5410897 | 0.78 | ADORA2A (0.61) | ADORA2AADORA2BADORA1 | |
| SCHEMBL3544439 | 0.75 | — | — | |
| SCHEMBL5013365 | 0.75 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL3547163 | 0.74 | ADORA2A (0.69) | ADORA2AADORA2BADORA1 | |
| SCHEMBL3547159 | 0.74 | ADORA2A (0.69) | ADORA2AADORA2BADORA1 | |
| SCHEMBL3547156 | 0.74 | ADORA2A (0.69) | ADORA2AADORA2BADORA1 | |
| SCHEMBL5012692 | 0.73 | ADORA2A (0.57) | ADORA2A | |
| SCHEMBL5012689 | 0.73 | ADORA2A (0.54) | ADORA2AADORA2BADORA1 | |
| SCHEMBL9325950 | 0.73 | ADORA2A (0.76) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633756-B1 | A2A ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN IDEC INC (US) | 2008-12-24 | — | — | EP | disclosed |
| EP-1633756-A2 | A2A ADENOSINE RECEPTOR ANTAGONISTS | Biogen Idec MA Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004092173-A2 | A2A ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | disclosed |