Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | XDH | P47989 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | ALPL | P05186 | 2/20 | 0.65 |
| ▸ | ALPI | P09923 | 2/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | KDM1A | O60341 | 2/20 | 0.65 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18530210 | 1.00 | P4HB (0.65) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL19281678 | 0.94 | P4HB (0.64) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL18530191 | 0.94 | KDM4E (0.72) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL18530250 | 0.94 | KDM4E (0.72) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL10617449 | 0.88 | P4HB (0.71) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL7204181 | 0.88 | P4HB (0.71) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL5793332 | 0.87 | P4HB (0.63) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL19439520 | 0.82 | P4HB (0.59) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL10619215 | 0.81 | P4HB (0.70) | P4HBKDM4EAKR1B1EPHX2GAA | |
| SCHEMBL5793331 | 0.80 | NQO2 (0.62) | P4HBKDM4EAKR1B1EPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |