Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744761 | 0.87 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL2937076 | 0.76 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5023793 | 0.76 | — | — | |
| SCHEMBL5307877 | 0.71 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL3541372 | 0.69 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL1075324 | 0.68 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL5746847 | 0.68 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL1712457 | 0.68 | TRPA1 (0.36) | KCNH2 | |
| SCHEMBL1712460 | 0.68 | TRPA1 (0.36) | KCNH2 | |
| SCHEMBL1723590 | 0.67 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001887-A1 | PYRROLO-QUINOXALINONE DERIVATIVES AS ANTIBACTERIALS | Glaxo Group Limited (GB) | 2008-12-17 | — | — | EP | disclosed |
| EP-1893581-A1 | SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES | Pfizer Limited (GB) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007115947-A1 | PYRROLO-QUINOXALINONE DERIVATIVES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
| WO-2006134468-A1 | SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES | PFIZER LIMITED (GB) | 2006-12-21 | — | — | WO | disclosed |