Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506693 | 1.00 | KDM4E (0.39) | KDM4EHTTRAPGEF3RAPGEF4HSD17B10 | |
| SCHEMBL3060327 | 1.00 | KDM4E (0.39) | KDM4EHTTRAPGEF3RAPGEF4HSD17B10 | |
| SCHEMBL3056872 | 0.83 | KDM4E (0.39) | KDM4EHTTHSD17B10MAPTKMT2A | |
| SCHEMBL4505828 | 0.81 | HTT (0.39) | KDM4EHTTHSD17B10MAPTKMT2A | |
| SCHEMBL3073265 | 0.80 | KDM4E (0.38) | KDM4EHTTHSD17B10MAPTKMT2A | |
| SCHEMBL3052855 | 0.80 | KDM4E (0.36) | KDM4EHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL2305202 | 0.80 | TSHR (0.38) | KDM4EHTTHSD17B10MAPTKMT2A | |
| SCHEMBL4518752 | 0.78 | KDM4E (0.35) | KDM4EHTTALDH1A1 | |
| SCHEMBL3052833 | 0.78 | HTT (0.33) | KDM4EHTTMAPTKMT2AGAA | |
| SCHEMBL3052839 | 0.78 | HTT (0.33) | KDM4EHTTMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |