⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027158 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL1442122 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL5162851 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL3028721 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL25819 | 1.00 | — | — | |
| SCHEMBL3025889 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL130984 | 1.00 | — | — | |
| SCHEMBL5162640 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL3030542 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL3029726 | 1.00 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1092 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354897-A | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2023-06-30 | — | — | CN | claimed |
| CN-116283520-A | Preparation method of aryl ketone, alpha-hydroxy ketone and alpha-amino ketone | 安庆莱霆光电科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-20210371417-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2021-12-02 | — | — | US | claimed |
| EP-3634962-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | claimed |
| CN-110997671-A | Azaindole compounds as histone methyltransferase inhibitors | 全球血液疗法股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-20180354947-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2018-12-13 | — | — | US | claimed |
| WO-2018226998-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2018-12-13 | — | — | WO | claimed |
| CN-107459439-A | Improved liquid phase alkylation process | 埃克森美孚化学专利公司 | 2017-12-12 | — | — | CN | claimed |
| EP-3057974-B1 | VINYLSILANES FOR USE IN FUNCTIONALIZED ELASTOMERIC POLYMERS | TRINSEO EUROPE GMBH (CH) | 2017-12-06 | — | — | EP | claimed |
| EP-0854724-A1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | Novartis AG (CH) | 1998-07-29 | — | — | EP | claimed |
| US-5733564-A | COMPOUNDS FOR BONE DISORDERS | LEIRAS OY (FI) | 1998-03-31 | — | — | US | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| WO-1997012619-A1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | NOVARTIS AG (CH) | 1997-04-10 | — | — | WO | claimed |
| EP-0600834-A1 | Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0550385-A1 | Oral pharmaceutical compositions containing derivatives of methane-diphosphonic acid and 18-crown-6 ethers | CIBA-GEIGY AG (CH) | 1993-07-07 | — | — | EP | claimed |
| EP-0407344-A2 | Pharmaceutical preparation for topical application | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | claimed |
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | claimed |
| US-4569994-A | Dibenzo[b,d]pyranyloxyaminopropanols | PENNWALT CORPORATION | 1986-02-11 | — | — | US | claimed |
| US-3956339-A | 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |