Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | DRD3 | P35462 | 7/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015794 | 1.00 | DRD2 (0.39) | DRD2DRD3HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL4849926 | 0.99 | DRD2 (0.38) | DRD2DRD3HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL4849923 | 0.99 | DRD2 (0.38) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL4856347 | 0.94 | DRD2 (0.38) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL4856358 | 0.94 | DRD2 (0.38) | DRD2DRD3HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL4859409 | 0.94 | DRD2 (0.37) | DRD2DRD3HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL4852943 | 0.94 | DRD2 (0.37) | DRD2DRD3HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL4852937 | 0.94 | DRD2 (0.37) | DRD2DRD3HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL4858129 | 0.93 | DRD2 (0.39) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL4250736 | 0.92 | DRD2 (0.38) | DRD2DRD3HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | claimed |
| EP-1698620-B1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | EISAI R&D MAN CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-7410971-B2 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| EP-1698620-A1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | Eisai Co., Ltd. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | CCR10, HRH3, HRH1 | DRD2 554/4885DRD3 315/4885HTR1A 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.