Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015837 | 1.00 | CHRM2 (0.38) | CHRM2SIGMAR1LSS | |
| SCHEMBL4805347 | 0.88 | CHRM2 (0.39) | CHRM2SIGMAR1LSS | |
| SCHEMBL4805353 | 0.88 | CHRM2 (0.39) | CHRM2SIGMAR1LSS | |
| SCHEMBL7207712 | 0.77 | CHRM2 (0.35) | CHRM2LSS | |
| SCHEMBL7210755 | 0.77 | CHRM2 (0.35) | CHRM2LSS | |
| SCHEMBL7209024 | 0.77 | CHRM2 (0.35) | CHRM2LSS | |
| SCHEMBL7210752 | 0.77 | CHRM2 (0.35) | CHRM2LSS | |
| SCHEMBL7209027 | 0.77 | CHRM2 (0.35) | CHRM2LSS | |
| SCHEMBL7207709 | 0.77 | CHRM2 (0.35) | CHRM2LSS | |
| SCHEMBL4800942 | 0.76 | CHRM2 (0.34) | CHRM2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-B1 | AMINOCYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |