Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 10/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501582 | 1.00 | RXRA (0.56) | RXRARXRBRXRGPIM1PIM2 | |
| SCHEMBL501583 | 1.00 | RXRA (0.56) | RXRARXRBRXRGPIM1PIM2 | |
| SCHEMBL501584 | 0.89 | RXRA (0.54) | RXRARXRBRXRGPIM1PIM2 | |
| SCHEMBL5492870 | 0.79 | GSK3B (0.49) | RXRAPIM1PIM2GSK3BHPGD | |
| SCHEMBL5492867 | 0.79 | GSK3B (0.49) | RXRAPIM1PIM2GSK3BHPGD | |
| SCHEMBL7461584 | 0.79 | GSK3B (0.49) | RXRAPIM1PIM2GSK3BHPGD | |
| SCHEMBL7461577 | 0.79 | GSK3B (0.49) | RXRAPIM1PIM2GSK3BHPGD | |
| SCHEMBL14492755 | 0.79 | GSK3B (0.49) | RXRAPIM1PIM2GSK3BHPGD | |
| SCHEMBL7458010 | 0.78 | PIM1 (0.52) | RXRAPIM1PIM2GSK3BHPGD | |
| SCHEMBL5487591 | 0.78 | PIM1 (0.52) | RXRAPIM1PIM2GSK3BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291492-A1 | METHOD FOR FORMING ORGAN | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-11-26 | — | — | US | claimed |
| US-20070161105-A1 | Method of forming organ | REASEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-07-12 | — | — | US | claimed |
| EP-1612264-A1 | ORGAN-FORMING METHOD | Research Foundation Itsuu Laboratory (JP) | 2006-01-04 | — | — | EP | claimed |
| US-8105833-B2 | Method for forming organ | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090291492-A1 | METHOD FOR FORMING ORGAN | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20070161105-A1 | Method of forming organ | REASEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-07-12 | — | — | US | disclosed |
| EP-1612264-A1 | ORGAN-FORMING METHOD | Research Foundation Itsuu Laboratory (JP) | 2006-01-04 | — | — | EP | disclosed |