Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4858030 | 0.99 | HTR1A (0.42) | HTR1AADRA1BADRA1DADRA1ACACNA1G | |
| Hydrochloric Acid SCHEMBL4849947 | 0.90 | HTR1A (0.46) | HTR1AADRA1BADRA1DADRA1AOPRL1 | |
| SCHEMBL4254249 | 0.89 | HTR1A (0.41) | HTR1AADRA1BADRA1DADRA1ACACNA1G | |
| Hydrochloric Acid SCHEMBL4856812 | 0.88 | HTR1A (0.45) | HTR1AADRA1BADRA1DADRA1ACACNA1G | |
| Hydrochloric Acid SCHEMBL4857990 | 0.88 | HTR1A (0.41) | HTR1AADRA1BADRA1DADRA1ACACNA1G | |
| SCHEMBL18092163 | 0.87 | HTR1A (0.52) | HTR1AADRA1BADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL4860608 | 0.86 | HTR1A (0.51) | HTR1AADRA1BADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL4857040 | 0.86 | HTR1A (0.37) | HTR1AADRA1BADRA1DADRA1ACACNA1G | |
| Hydrochloric Acid SCHEMBL4855962 | 0.85 | HTR1A (0.50) | HTR1AADRA1BADRA1DADRA1AOPRL1 | |
| Hydrochloric Acid SCHEMBL4856020 | 0.84 | HTR1A (0.42) | HTR1AADRA1BOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | claimed |
| US-7410971-B2 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | CCR10, HRH3, HRH1 | HTR1A 1433/4885ADRA1B 304/4885ADRA1D 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.