Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.90 |
| ▸ | MAPT | P10636 | 3/20 | 0.90 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.90 |
| ▸ | MEN1 | O00255 | 2/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.90 |
| ▸ | LMNA | P02545 | 1/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.90 |
| ▸ | PKM | P14618 | 1/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.90 |
| ▸ | TSHR | P16473 | 1/20 | 0.90 |
| ▸ | THPO | P40225 | 1/20 | 0.90 |
| ▸ | BLM | P54132 | 1/20 | 0.90 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.90 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.90 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096660 | 0.98 | ALDH1A1 (0.88) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| SCHEMBL10662786 | 0.98 | ALDH1A1 (0.88) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| SCHEMBL10660431 | 0.98 | ALDH1A1 (0.88) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| SCHEMBL10662805 | 0.98 | ALDH1A1 (0.88) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| SCHEMBL10986992 | 0.98 | ALDH1A1 (0.88) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| SCHEMBL2689054 | 0.98 | ALDH1A1 (0.88) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| SCHEMBL2271999 | 0.97 | ALDH1A1 (0.85) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| Fusaric Acid SCHEMBL29406685 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| Fusaric Acid SCHEMBL8606376 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTNFKB1MEN1KMT2A | |
| Fusaric Acid SCHEMBL178006 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTNFKB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101001-B1 | DEUTERATED CATECHOLAMINE DERIVATIVES AND MEDICAMENTS COMPRISING SAID COMPOUNDS | TEVA PHARMACEUTICALS INT GMBH (CH) | 2020-04-01 | — | — | EP | claimed |
| EP-0066242-B1 | TOCOPHERYL ESTER OF 5-SUBSTITUTED PICOLINIC ACID, PROCESS FOR ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING IT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | claimed |
| US-4443459-A | α-Tocopheryl ester of 5-substituted picolinic acid and hypotensive composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-04-17 | — | — | US | claimed |
| EP-0066242-A1 | Tocopheryl ester of 5-substituted picolinic acid, process for its production, and pharmaceutical composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-12-08 | — | — | EP | claimed |
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-03-27 | — | — | US | disclosed |
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-03-27 | — | — | US | disclosed |
| EP-1824822-A2 | NOVEL 4-AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006056930-A2 | NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-01 | — | — | WO | disclosed |
| WO-2006056930-A2 | NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-01 | — | — | WO | disclosed |
| EP-0066242-B1 | TOCOPHERYL ESTER OF 5-SUBSTITUTED PICOLINIC ACID, PROCESS FOR ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING IT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | disclosed |
| US-4443459-A | α-Tocopheryl ester of 5-substituted picolinic acid and hypotensive composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0066242-A1 | Tocopheryl ester of 5-substituted picolinic acid, process for its production, and pharmaceutical composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | METAP1, DNPEP, PEPD | ALDH1A1 1303/4885MAPT 3156/4885NFKB1 1951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.