Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016248 | 0.86 | RAB9A (0.56) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL27645220 | 0.80 | RAB9A (0.57) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL7959699 | 0.73 | RAB9A (0.71) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL27645188 | 0.73 | RAB9A (0.75) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL7760900 | 0.72 | RAB9A (1.00) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL5544112 | 0.71 | MAPT (0.74) | DRD2GAAKDM4E | |
| Hydrochloric Acid SCHEMBL7963191 | 0.71 | RAB9A (0.81) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL7761263 | 0.71 | RAB9A (0.81) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL5013351 | 0.70 | RAB9A (0.56) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| Oxalic Acid SCHEMBL7762758 | 0.70 | RAB9A (0.66) | RAB9AMEN1KMT2ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |