SCHEMBL5016408

SCHEMBL5016408

CCCNC(=O)c1nc([Si](OC)(OC)OC)c[nH]1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 2/20 0.34
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ESR1 P03372 1/20 0.34
JMJD7 P0C870 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
STAT3 P40763 1/20 0.34
STAT1 P42224 1/20 0.34
ROCK2 O75116 1/20 0.33
DPP4 P27487 1/20 0.33
PKM P14618 1/20 0.33
CHEK1 O14757 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165962 0.77 POLB (0.41) POLBL3MBTL1NPC1HPGDALDH1A1
SCHEMBL164028 0.69 TSHR (0.46) L3MBTL1RAB9ASMN1; SMN2HPGDALOX15
SCHEMBL161198 0.69 TSHR (0.46) L3MBTL1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL1848067 0.66 POLB (0.41) POLBL3MBTL1NPC1TP53ALDH1A1
SCHEMBL6663162 0.66 NPC1 (0.42) POLBL3MBTL1NPC1RAB9ASMN1; SMN2
SCHEMBL8580616 0.65
SCHEMBL160288 0.65 NPC1 (0.43) POLBL3MBTL1NPC1RAB9ASMN1; SMN2
SCHEMBL159512 0.64 PIN1 (0.36) POLBL3MBTL1NPC1HPGDALOX15
SCHEMBL6639419 0.64 NAMPT (0.46) POLBL3MBTL1SMN1; SMN2HPGDALDH1A1
SCHEMBL159511 0.64 PIN1 (0.36) L3MBTL1NPC1HPGDALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954760-A2 CATALYTICALLY ACTIVE COMPOSITION, MEMBRANE-ELECTRODE UNIT COMPRISING THE SAME, AND CATALYST COMPRISING/MADE OF THE SAME Universität Bremen (DE) 2008-08-13 EP claimed
WO-2007031346-A2 CATALYTICALLY ACTIVE COMPOSITION, MEMBRANE-ELECTRODE UNIT COMPRISING THE SAME, AND CATALYST COMPRISING/MADE OF THE SAME UNIVERSITÄT BREMEN (DE) 2007-03-22 WO claimed
EP-1954760-A2 CATALYTICALLY ACTIVE COMPOSITION, MEMBRANE-ELECTRODE UNIT COMPRISING THE SAME, AND CATALYST COMPRISING/MADE OF THE SAME Universität Bremen (DE) 2008-08-13 EP disclosed
WO-2007031346-A2 CATALYTICALLY ACTIVE COMPOSITION, MEMBRANE-ELECTRODE UNIT COMPRISING THE SAME, AND CATALYST COMPRISING/MADE OF THE SAME UNIVERSITÄT BREMEN (DE) 2007-03-22 WO disclosed