SCHEMBL501649

SCHEMBL501649

O=C(O)CCNC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320940 0.82 PRMT1 (0.58)
SCHEMBL16938643 0.81 PRMT1 (0.64)
SCHEMBL29916467 0.80 PRMT1 (0.70)
SCHEMBL4047411 0.79 CYP2D6 (0.45)
SCHEMBL9717468 0.79 ECE1 (0.81)
SCHEMBL9717431 0.79 ECE1 (0.65)
SCHEMBL10770813 0.79
SCHEMBL10798199 0.79
SCHEMBL6065930 0.78 PRMT1 (0.74)
SCHEMBL29908844 0.78 PRMT1 (0.74)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481897-B9 SILICONE HYDROGELS COMPRISING POLYAMIDES JOHNSON & JOHNSON VISION CARE (US) 2024-04-10 EP claimed
EP-3481897-B1 SILICONE HYDROGELS COMPRISING POLYAMIDES JOHNSON & JOHNSON VISION CARE (US) 2024-01-03 EP claimed
EP-3481877-B9 SILICONE HYDROGELS COMPRISING HIGH LEVELS OF POLYAMIDES JOHNSON & JOHNSON VISION CARE (US) 2023-09-27 EP claimed
EP-3481877-B1 SILICONE HYDROGELS COMPRISING HIGH LEVELS OF POLYAMIDES JOHNSON & JOHNSON VISION CARE (US) 2023-06-21 EP claimed
EP-3126415-B1 SILICONE ACRYLAMIDE COPOLYMER JOHNSON & JOHNSON VISION CARE (US) 2021-12-15 EP claimed
EP-2794727-B2 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE (US) 2020-10-28 EP claimed
CN-111620909-A Prodrug of Reidesvir, preparation method and application thereof 广东中科药物研究有限公司 2020-09-04 CN claimed
EP-3126416-B1 SILICONE ACRYLAMIDE COPOLYMER JOHNSON & JOHNSON VISION CARE (US) 2019-08-07 EP claimed
EP-2794724-B9 SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES JOHNSON & JOHNSON VISION CARE (US) 2019-01-09 EP claimed
CN-109081883-A A kind of thermoplasticity butyl rubber and preparation method 北京化工大学 2018-12-25 CN claimed
EP-2705073-B1 MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT JOHNSON & JOHNSON VISION CARE (US) 2018-01-10 EP claimed
US-9617423-B2 Macroinitiator containing hydrophobic segment JOHNSON & JOHNSON VISION CARE, INC. (US) 2017-04-11 US claimed
EP-2794726-B1 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY JOHNSON & JOHNSON VISION CARE (US) 2016-10-26 EP claimed
US-20160194497-A1 MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT JOHNSON & JOHNSON VISION CARE (US) 2016-07-07 US claimed
US-9321890-B2 Macroinitiator containing hydrophobic segment JOHNSON & JOHNSON VISION CARE, INC. (US) 2016-04-26 US claimed
US-20140296368-A1 MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT JOHNSON & JOHNSON VISION CARE (US) 2014-10-02 US claimed
EP-2705073-A1 MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT Johnson & Johnson Vision Care Inc. (US) 2014-03-12 EP claimed
WO-2012151134-A1 MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT JOHNSON & JOHNSON VISION CARE, INC. (US) 2012-11-08 WO claimed
US-20120283381-A1 MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT JOHNSON & JOHNSON VISION CARE, INC. 2012-11-08 US claimed
EP-1809344-B1 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2010-01-20 EP claimed