SCHEMBL4047411

SCHEMBL4047411

O=C(O)NCCNC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 2/20 0.40
EGLN1 Q9GZT9 2/20 0.40
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
TSHR P16473 3/20 0.38
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 3/20 0.33
KDM5C P41229 2/20 0.33
PHF8 Q9UPP1 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
KDM6B O15054 1/20 0.33
FOLH1 Q04609 1/20 0.33
PRMT1 Q99873 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31613206 0.96 CYP2D6 (0.43) CYP2D6CYP2C19LMNAEGLN1LDHA
Ethylene SCHEMBL8519352 0.93 CYP2D6 (0.41) CYP2D6CYP2C19LMNAEGLN1LDHA
SCHEMBL2240590 0.89 CA3 (0.42) CYP2D6CYP2C19LMNAEGLN1LDHA
SCHEMBL18886295 0.89 PRMT1 (0.46) CYP2D6CYP2C19LMNAEGLN1LDHA
SCHEMBL3174690 0.85 KDM4E (0.50) CYP2D6CYP2C19POLBKDM4EPRMT1
SCHEMBL8958360 0.85 KDM4E (0.43) CYP2D6CYP2C19POLBKDM4EPRMT1
SCHEMBL1863794 0.84
SCHEMBL6421935 0.84
SCHEMBL3557960 0.84 KDM4E (0.57) CYP2D6CYP2C19TSHRUSP2KDM4E
SCHEMBL15871737 0.82 KDM4E (0.55) POLBKDM4EPRMT1MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841496-B1 RUBBER COMPOSITIONS ALLNEX GERMANY GMBH (DE) 2022-10-26 EP claimed
CN-113563493-A Hydrophobic polysaccharide and preparation method and application thereof 蚌埠医学院 2021-10-29 CN claimed
CN-104245814-B Rubber composition 湛新德国有限公司 2016-11-09 CN claimed
CN-104245814-A Rubber compositions CYTEC SURFACE SPECIALTIES GERMANY GMBH 2014-12-24 CN claimed
EP-2710160-A2 RECOVERY REACTOR UPL Limited (IN) 2014-03-26 EP claimed
WO-2012160494-A2 RECOVERY REACTOR UNITED PHOSPHORUS LIMITED (IN) 2012-11-29 WO claimed
US-4971598-A Reaction products of alkenyl succinimides with ethylenediamine carboxy acids as fuel detergents MOBIL OIL CORPORATION (US) 1990-11-20 US claimed
EP-0011049-B1 AMINOPLAST RESIN, ITS PREPARATION AND ITS USE CIBA-GEIGY AG (CH) 1982-08-04 EP claimed
EP-0011049-A1 Aminoplast resin, its preparation and its use CIBA-GEIGY AG (CH) 1980-05-14 EP claimed
JP-52117423-A None JP disclosed
CN-119947760-A Antibody drug complexes comprising Toll-like receptor 7/8 dual agonist compounds 安斯泰来制药株式会社 2025-05-06 CN disclosed
CN-113453724-B Sulfonylmaleimide-based linkers and corresponding conjugates 皮埃尔法布雷医药公司 2025-02-25 CN disclosed
US-20240398963-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) 2024-12-05 US disclosed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN disclosed
US-4897255-A Metal radionuclide labeled proteins for diagnosis and therapy NEORX CORPORATION (US) 1990-01-30 US disclosed
EP-0284071-A2 Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy NEORX CORPORATION (US) 1988-09-28 EP disclosed
EP-0188256-A2 Metal radionuclide labeled proteins for diagnosis and therapy NeoRx (US) 1986-07-23 EP disclosed
EP-0011049-B1 AMINOPLAST RESIN, ITS PREPARATION AND ITS USE CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed
EP-0011049-A1 Aminoplast resin, its preparation and its use CIBA-GEIGY AG (CH) 1980-05-14 EP disclosed
JP-S52117423-A AGRICULTURAL AND HORTICULTURAL MICROBICIDAL COMPOSITION KUMIAI CHEM IND CO LTD 1977-10-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398963-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF TIE1, KDR, TEK CYP2D6 4318/4885CYP2C19 4838/4885LMNA 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.