Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496059 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL2150014 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL15071024 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL5921881 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL2149478 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL5788530 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL2149399 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL3742624 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL7156909 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 | |
| SCHEMBL3829000 | 1.00 | CES2 (0.58) | CES2CES1LMNANAAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080102127-A1 | HYBRID LIPID-POLYMER NANOPARTICULATE DELIVERY COMPOSITION | ALPHARX INC. (CA) | 2008-05-01 | — | — | US | disclosed |
| US-20050255133-A1 | Topical composition for acne treatment | ALPHARX INC. (CA) | 2005-11-17 | — | — | US | disclosed |