Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603383 | 0.83 | GRIK1 (0.51) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL5603663 | 0.83 | GRIK1 (0.51) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL19267595 | 0.81 | GRIK1 (0.59) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL28632498 | 0.81 | GRIK1 (0.59) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL11339081 | 0.81 | GRIK1 (0.59) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL2513155 | 0.79 | GRIK1 (0.58) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL28074097 | 0.79 | GRIK1 (0.58) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL28982179 | 0.79 | CA2 (0.59) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL26597271 | 0.78 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL29036745 | 0.77 | CA2 (0.57) | GRIK1GRIK2SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527115-B1 | POLYURETHANE COMPOSITIONS CONTAINING POLYALDIMINE | SIKA TECHNOLOGY AG (CH) | 2008-04-23 | — | — | EP | disclosed |
| EP-1527044-B1 | POLYALDIMINES | SIKA TECHNOLOGY AG (CH) | 2007-11-14 | — | — | EP | disclosed |
| EP-1527115-A1 | POLYURETHANE COMPOSITIONS CONTAINING POLYALDIMINE | Sika Technology AG (CH) | 2005-05-04 | — | — | EP | disclosed |
| EP-1527044-A1 | POLYALDIMINES | Sika Technology AG (CH) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004013088-A1 | POLYALDIMINES | SIKA TECHNOLOGY AG (CH) | 2004-02-12 | — | — | WO | disclosed |
| WO-2004013200-A1 | POLYURETHANE COMPOSITIONS CONTAINING POLYALDIMINE | SIKA TECHNOLOGY AG (CH) | 2004-02-12 | — | — | WO | disclosed |