SCHEMBL501868

SCHEMBL501868

O=C(OCCN1CCCCC1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.75
MEN1 O00255 2/20 0.75
NPSR1 Q6W5P4 1/20 0.65
HPGD P15428 1/20 0.63
CYP2D6 P10635 2/20 0.62
ALDH1A1 P00352 4/20 0.59
LTA4H P09960 1/20 0.58
GFER P55789 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
TSHR P16473 1/20 0.58
THPO P40225 1/20 0.58
MAPK1 P28482 1/20 0.57
PMP22 Q01453 1/20 0.56
KDM4E B2RXH2 1/20 0.56
PSMB1 P20618 1/20 0.56
PSMB5 P28074 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8481680 0.98 KMT2A (0.73) KMT2AMEN1NPSR1HPGDCYP2D6
Water SCHEMBL8479966 0.98 KMT2A (0.73) KMT2AMEN1NPSR1HPGDCYP2D6
SCHEMBL501862 0.98 KMT2A (0.72) KMT2AMEN1NPSR1HPGDCYP2D6
Hydrochloric Acid SCHEMBL8624619 0.97 KMT2A (0.70) KMT2AMEN1NPSR1HPGDCYP2D6
SCHEMBL501887 0.91 KMT2A (0.72) KMT2AMEN1NPSR1HPGDCYP2D6
SCHEMBL8355590 0.91 CYP2D6 (0.76) KMT2AMEN1CYP2D6ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL8622970 0.89 CYP2D6 (0.74) KMT2AMEN1NPSR1HPGDCYP2D6
SCHEMBL501795 0.89 KMT2A (0.69) KMT2AMEN1NPSR1HPGDCYP2D6
SCHEMBL14106811 0.86 KMT2A (1.00) KMT2AMEN1NPSR1HPGDCYP2D6
SCHEMBL2663560 0.86 HRH3 (0.71) KMT2AMEN1NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958969-A OSTEOPOROSIS ELI LILLY AND COMPANY (US) 1999-09-28 US claimed
US-11829067-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-28 US disclosed
US-11829067-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-28 US disclosed
EP-2033966-B1 Novel photoacid generators, resist compositons, and patterning processes SHINETSU CHEMICAL CO (JP) 2015-07-29 EP disclosed
US-8945809-B2 Fluorinated monomer, fluorinated polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-02-03 US disclosed
US-8933251-B2 Fluorinated monomer of cyclic acetal structure, polymer, resist protective coating composition, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-13 US disclosed
US-8728707-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-20 US disclosed
US-8728707-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-20 US disclosed
US-8609889-B2 Photoacid generator, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-12-17 US disclosed
US-8568956-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-29 US disclosed
CN-1277809-C Benzal indone and benzyl indone derivative(s), and its preparing method and use UNIV ZHEJIANG (CN) 2006-10-04 CN disclosed
CN-1709860-A Benzal indone and benzyl indone derivative(s), and its preparing method and use UNIV ZHEJIANG (CN) 2005-12-21 CN disclosed
US-5958969-A OSTEOPOROSIS ELI LILLY AND COMPANY (US) 1999-09-28 US disclosed
US-5948795-A PLASMINOGEN ACTIVATOR INHIBITOR ELI LILLY AND COMPANY (US) 1999-09-07 US disclosed
US-5948796-A OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS ELI LILLY AND COMPANY (US) 1999-09-07 US disclosed
US-5856341-A INHIBITING BONE LOSS OR BONE RESORPTION, PARTICULARLY OSTEOPOROSIS, CARDIOVASCULAR-RELATED PATHOLOGICAL CONDITIONS INCLUDING HYPERLIPIDEMIA, ESTROGEN-DEPENDENT CANCER ELI LILLY AND COMPANY (US) 1999-01-05 US disclosed
US-5843984-A Sulfated benzothiophene derivatives, methods of use and formulations containing same ELI LILLY AND COMPANY (US) 1998-12-01 US disclosed
US-5827853-A MIXTURE CONTAINING PRODUCT FROM FERMENTATION BY STREPTOMYCES FOR TOPICAL APPLICATION TO SKIN OR HAIR, TO IMPROVE TEXTURE, SURFACE SMOOTHNESS, FIRMNESS SANOFI (FR) 1998-10-27 US disclosed
US-5798351-A USEFUL FOR INHIBITING BONE LOSS, LOWERING SEUM CHOLESTEROL LEVELS AND TREATING HORMONE DEPENDENT MAMMALIAN BREAST AND UTERINE CANCER ELI LILLY AND COMPANY (US) 1998-08-25 US disclosed
US-5731342-A FOR TREATING AND PREVENTING POSTMENOPAUSAL SYNDROME AND BREAST CANCER ELI LILLY AND COMPANY (US) 1998-03-24 US disclosed