Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | BRD4 | O60885 | 1/20 | 0.67 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127668 | 0.90 | DRD3 (0.64) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL17189834 | 0.90 | KDM4E (0.63) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| Naldixic Acid SCHEMBL10330758 | 0.90 | DRD3 (0.64) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL13007994 | 0.90 | DRD3 (0.61) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3806524 | 0.89 | DRD3 (0.60) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| 7-Amino-Fluoroquinone SCHEMBL10679457 | 0.89 | DRD3 (0.63) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29548224 | 0.89 | DRD3 (0.63) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6693005 | 0.89 | DRD3 (0.63) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3809668 | 0.89 | DRD3 (0.63) | DRD3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5434181 | 0.89 | DRD3 (0.63) | DRD3ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484451-A | Stable isotope labeled norfloxacin and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| US-4264604-A | Quinolonecarboxylic acid derivatives as bactericides | CIBA-GEIGY CORPORATION (US) | 1981-04-28 | — | — | US | claimed |
| EP-3630779-B1 | ANTIBIOTIC RESISTANCE BREAKERS | KING S COLLEGE LONDON (GB) | 2025-09-03 | — | — | EP | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| CN-110869373-B | Antibiotic resistance disruptors | 伦敦皇家学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-111484451-A | Stable isotope labeled norfloxacin and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111484451-A | Stable isotope labeled norfloxacin and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111320581-A | Synthesis method of quinoline carboxylic ester | 山东省联合农药工业有限公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-110869373-A | Antibiotic resistance disruptors | 伦敦皇家学院 | 2020-03-06 | — | — | CN | disclosed |
| EP-0230053-A2 | 7-(Substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4665079-A | QUINOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0215650-A2 | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4638067-A | NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS | WARNER-LAMBERT CO. (US) | 1987-01-20 | — | — | US | disclosed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4473568-A | ANTIBACTERIAL AGENTS | WARNER LAMBERT COMPANY (US) | 1984-09-25 | — | — | US | disclosed |
| EP-0106489-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746116-B2 | Antibiotic resistance breakers | ABCC1, ARL1, AKR1C3 | DRD3 594/4885ALDH1A1 481/4885HPGD 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.