Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501895 | 0.89 | DRD3 (0.68) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7127668 | 0.85 | DRD3 (0.64) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| Naldixic Acid SCHEMBL10330758 | 0.85 | DRD3 (0.64) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6687806 | 0.85 | LMNA (0.67) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3809668 | 0.84 | DRD3 (0.63) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| 7-Amino-Fluoroquinone SCHEMBL10679457 | 0.84 | DRD3 (0.63) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5434181 | 0.84 | DRD3 (0.63) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29548224 | 0.84 | DRD3 (0.63) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL541723 | 0.83 | DRD3 (0.61) | DRD3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL541724 | 0.83 | DRD3 (0.61) | DRD3HPGDALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101584-A1 | MACROLIDES SUBSTITUTED AT THE 3-POSITION HAVING ANTIMICROBIAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |