Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114625 | 1.00 | SLC1A1 (0.48) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| SCHEMBL9782083 | 1.00 | SLC1A1 (0.48) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4082393 | 0.98 | SLC1A1 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| SCHEMBL16238395 | 0.85 | SMN1; SMN2 (0.40) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| SCHEMBL12069779 | 0.85 | SMN1; SMN2 (0.40) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| SCHEMBL2498988 | 0.85 | SMN1; SMN2 (0.40) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| SCHEMBL2498989 | 0.85 | SMN1; SMN2 (0.40) | SLC1A1SLC1A3SLC1A2SLC7A5SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10858237 | 0.83 | SMN1; SMN2 (0.39) | SLC1A1SLC1A3SLC1A2SMN1; SMN2LTA4H | |
| Hydrochloric Acid SCHEMBL16238696 | 0.83 | SMN1; SMN2 (0.39) | SLC1A1SLC1A3SLC1A2SMN1; SMN2LTA4H | |
| Hydrochloric Acid SCHEMBL16238384 | 0.83 | SMN1; SMN2 (0.39) | SLC1A1SLC1A3SLC1A2SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2010054102-A2 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | SLC1A1 1681/4885SLC1A3 2094/4885SLC1A2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.