Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 15/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15306521 | 0.77 | AVPR1B (0.39) | AVPR1BALDH1A1PIK3CDPIK3R2 | |
| SCHEMBL3696680 | 0.77 | PIK3CD (0.48) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL15336733 | 0.77 | PIK3R2 (0.38) | AVPR1BALDH1A1PIK3CDPIK3R2PIK3CG | |
| SCHEMBL3696676 | 0.77 | PIK3CD (0.48) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL4535138 | 0.77 | SIGMAR1 (0.41) | AVPR1BPIK3CDPIK3R2PIK3CGSIGMAR1 | |
| SCHEMBL3695237 | 0.77 | SIGMAR1 (0.41) | AVPR1BPIK3CDPIK3R2PIK3CGSIGMAR1 | |
| SCHEMBL16412325 | 0.75 | AVPR1B (0.39) | AVPR1BALDH1A1PIK3CDPIK3R2PIK3CG | |
| SCHEMBL4569391 | 0.73 | PIK3CD (0.42) | AVPR1BPIK3CDPIK3R2PIK3CG | |
| SCHEMBL16269981 | 0.73 | PIK3CD (0.38) | AVPR1BALDH1A1LMNAPIK3CDPIK3R2 | |
| SCHEMBL4569341 | 0.71 | PIK3CD (0.45) | USP2ALDH1A1LMNAHTTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064973-A2 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |