Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 11/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019662 | 0.91 | IL2 (0.40) | KMT2ACRACR2AMAP3K5HTR1FIL2 | |
| SCHEMBL5019603 | 0.89 | KMT2A (0.39) | KMT2AWDR5MAP3K5WNT1GSK3B | |
| SCHEMBL5019607 | 0.89 | STIM1 (0.42) | CRACR2AMAP3K5HTR1FIL2NPC1 | |
| SCHEMBL5019579 | 0.83 | KMT2A (0.39) | KMT2AMAP3K5WNT1GSK3BDYRK1A | |
| SCHEMBL3826508 | 0.82 | KMT2A (0.47) | KMT2AMAP3K5WNT1GSK3BDYRK1A | |
| SCHEMBL3825366 | 0.80 | IL2 (0.44) | KMT2AMAP3K5HTR1AHTR1FIL2 | |
| SCHEMBL4999197 | 0.78 | IL2 (0.41) | KMT2AMAP3K5HTR1AHTR1FIL2 | |
| SCHEMBL8186422 | 0.77 | IL2 (0.40) | KMT2AMAP3K5WNT1GSK3BDYRK1A | |
| SCHEMBL12650398 | 0.77 | IL2 (0.40) | KMT2AMAP3K5WNT1GSK3BDYRK1A | |
| SCHEMBL3824488 | 0.77 | IL2 (0.42) | KMT2AHTR1FIL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |