Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880660 | 0.82 | SRC (0.58) | SRCL3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL310184 | 0.82 | SRC (0.58) | SRCL3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL6933635 | 0.82 | SRC (0.58) | SRCL3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL676524 | 0.82 | SRC (0.58) | SRCL3MBTL1TDP1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL29186320 | 0.80 | SRC (0.56) | SRCL3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL19212985 | 0.80 | SRC (0.56) | SRCL3MBTL1TDP1KDM4EHPGD | |
| Triphenyl Phosphate SCHEMBL11314242 | 0.80 | CYP3A4 (0.56) | SRCL3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL1363549 | 0.78 | SRC (0.67) | SRCL3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL29227303 | 0.78 | HPGD (0.55) | SRCL3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL4073045 | 0.78 | SRC (0.54) | SRCL3MBTL1TDP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062870-A1 | URACYL SPIROOXETANE NUCLEOSIDE PHOSPHORAMIDATES | JANSSEN PRODUCTS, LP (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062869-A1 | URACYL SPIROOXETANE NUCLEOSIDE PHOSPHORAMIDATES | JANSSEN PRODUCTS, LP (US) | 2012-05-18 | — | — | WO | disclosed |