SCHEMBL5019791

SCHEMBL5019791

O=c1c2ccc(-c3ccccc3)cc2sc2cc(-c3ccccc3)ccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.46
KDM4E B2RXH2 2/20 0.44
PIK3CA P42336 1/20 0.43
PI4KA P42356 1/20 0.43
PI4KB Q9UBF8 1/20 0.43
TNKS2 Q9H2K2 1/20 0.42
PTPN1 P18031 3/20 0.41
PTPN2 P17706 2/20 0.41
RAB9A P51151 3/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 3/20 0.41
NPC1 O15118 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41
GALK1 P51570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31124705 1.00 LIMK1 (0.46) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL5019798 0.96 LIMK1 (0.44) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL5019871 0.96 LIMK1 (0.44) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL5019868 0.96 LIMK1 (0.44) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL15216399 0.94 KDM4E (0.53) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL12562737 0.87 LIMK1 (0.51) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL10110898 0.87 LIMK1 (0.51) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL15216401 0.86 KDM4E (0.47) LIMK1KDM4ERAB9AMAPTLMNA
SCHEMBL20287449 0.86 APP (0.40) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL28459453 0.84 KDM4E (0.44) LIMK1KDM4EPIK3CAPI4KAPI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
WO-2012063751-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-18 WO disclosed