SCHEMBL15216401

SCHEMBL15216401

O=c1c2ccc(-c3ccc4c5ccccc5c5ccccc5c4c3)cc2sc2cc(-c3ccc4c5ccccc5c5ccccc5c4c3)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 9/20 0.44
MAPT P10636 7/20 0.44
RAB9A P51151 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
NPC1 O15118 3/20 0.44
HPGD P15428 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
POLB P06746 3/20 0.38
HCRTR1 O43613 2/20 0.38
LMNA P02545 1/20 0.38
GPR3 P46089 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 1/20 0.37
LIMK1 P53667 1/20 0.36
ALOX15 P16050 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5019777 0.89 KDM4E (0.56) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL31124705 0.86 LIMK1 (0.46) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL5019791 0.86 LIMK1 (0.46) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL15216399 0.85 KDM4E (0.53) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL5019876 0.84 KDM4E (0.57) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL5019875 0.84 KDM4E (0.57) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL30911275 0.84 GPR3 (0.58) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL12175603 0.84 GPR3 (0.58) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL31017615 0.84 GPR3 (0.58) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL5019868 0.83 LIMK1 (0.44) KDM4EALDH1A1MAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed