SCHEMBL5019863

SCHEMBL5019863

O=c1c2cc(-c3ccc(-c4ccccc4)cc3)ccc2sc2ccc(-c3ccc(-c4ccccc4)cc3)cc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
MAPT P10636 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ALDH1A1 P00352 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
LIMK1 P53667 1/20 0.46
PIM3 Q86V86 2/20 0.45
PIM1 P11309 1/20 0.43
PIM2 Q9P1W9 1/20 0.43
PTPN1 P18031 2/20 0.41
PTPN2 P17706 1/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5019864 1.00 KDM4E (0.53) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL5019862 0.96 KDM4E (0.50) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL5019911 0.96 KDM4E (0.50) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL5019788 0.96 KDM4E (0.50) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL22172013 0.94 KDM4E (0.62) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL1614826 0.94 KDM4E (0.62) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL29397550 0.94 KDM4E (0.62) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL22171902 0.91 KDM4E (0.58) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL5019905 0.90 KDM4E (0.57) KDM4ERAB9ANPC1MAPTL3MBTL1
SCHEMBL6070519 0.90 KDM4E (0.71) KDM4ERAB9ANPC1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
WO-2012063751-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-18 WO disclosed