Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24210393 | 0.90 | KDM4E (0.54) | KDM4ECYP1A2ADORA3MAPTLMNA | |
| SCHEMBL5019864 | 0.90 | KDM4E (0.53) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL5019863 | 0.90 | KDM4E (0.53) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL5019788 | 0.86 | KDM4E (0.50) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL5019862 | 0.86 | KDM4E (0.50) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL5019911 | 0.86 | KDM4E (0.50) | KDM4EMAPTLMNAMEN1KMT2A | |
| Benzene SCHEMBL28210953 | 0.85 | KDM4E (0.96) | KDM4ECYP1A2MAPTLMNAIDO1 | |
| SCHEMBL22172013 | 0.85 | KDM4E (0.62) | KDM4ECYP1A2MAPTLMNAMEN1 | |
| SCHEMBL1614826 | 0.85 | KDM4E (0.62) | KDM4ECYP1A2MAPTLMNAMEN1 | |
| SCHEMBL29397550 | 0.85 | KDM4E (0.62) | KDM4ECYP1A2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126011-B2 | Reacting 2-chlorothiobenzoyl chloride with aromatic compound; drug for psychological disorder therapy; photopolymerization sensitizer | PROM LIMITED (GB) | 2006-10-24 | — | — | US | disclosed |
| US-20030229233-A1 | Process for the preparation of thioxanthones | PROM LIMITED (GB) | 2003-12-11 | — | — | US | disclosed |
| US-4101558-A | Process for preparing thioxanthones | THE SHERWIN-WILLIAMS COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229233-A1 | Process for the preparation of thioxanthones | TST, TPST2, SULT2A1 | KDM4E 1374/4885CYP1A2 70/4885ADORA3 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.