Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.71 |
| ▸ | RAMP1 | O60894 | 14/20 | 0.71 |
| ▸ | CALCB | P10092 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4567286 | 0.83 | CALCRL (1.00) | CALCRLRAMP1 | |
| SCHEMBL14173337 | 0.83 | CALCRL (1.00) | CALCRLRAMP1 | |
| SCHEMBL18465596 | 0.82 | CALCRL (0.70) | CALCRLRAMP1 | |
| SCHEMBL13376820 | 0.77 | CALCRL (0.67) | CALCRLRAMP1 | |
| SCHEMBL14173340 | 0.76 | CALCRL (1.00) | CALCRLRAMP1 | |
| SCHEMBL4570719 | 0.76 | CALCRL (1.00) | CALCRLRAMP1 | |
| SCHEMBL21350996 | 0.76 | CALCRL (1.00) | CALCRLRAMP1 | |
| SCHEMBL4567285 | 0.75 | CALCRL (0.85) | CALCRLRAMP1 | |
| SCHEMBL18465478 | 0.74 | CALCRL (0.70) | CALCRLRAMP1 | |
| SCHEMBL13376819 | 0.73 | SLC6A12 (0.53) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064910-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2012-05-18 | — | — | WO | disclosed |