Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020719 | 0.96 | MAOB (0.55) | CA2LMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL18798798 | 0.94 | MAPT (0.58) | CA2LMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL25676 | 0.87 | CES1 (0.64) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1621316 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29642911 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| Methane SCHEMBL2335788 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| SCHEMBL4165526 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3651517 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| Phosphine SCHEMBL29287353 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 | |
| SCHEMBL3927471 | 0.85 | CES1 (0.61) | CA2HDAC8MAPK1HDAC6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209847-B | Method for preparing amide compound under catalysis of ionic liquid in high-pressure environment | 烟台大学 | 2022-12-23 | — | — | CN | disclosed |
| US-9636298-B2 | Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs | METHYLGENE INC (CA) | 2017-05-02 | — | — | US | disclosed |
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |
| EP-1233958-B1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC (CA) | 2011-06-29 | — | — | EP | disclosed |