SCHEMBL5020902

SCHEMBL5020902

CCCCNC(=O)NC1CCCCC1

nearest known ligand 0.96

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 13/20 0.90
EPHX2 P34913 6/20 0.87
KDM4E B2RXH2 1/20 0.80
ALDH1A1 P00352 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14423989 0.98 EPHX1 (0.87) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL7440101 0.95 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL26677285 0.95 EPHX1 (0.87) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL12196095 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL652844 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL7561514 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL4997375 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL1059134 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL12196099 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1
SCHEMBL12196092 0.93 EPHX1 (1.00) EPHX1EPHX2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846710-B2 Method of preferentially inducing the biosynthesis of interferon 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-8846710-B2 Method of preferentially inducing the biosynthesis of interferon 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-8178677-B2 Hydroxyalkyl substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-8178677-B2 Hydroxyalkyl substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-7732416-B2 For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection MERIAL LIMITED (US) 2010-06-08 US disclosed
US-7605134-B2 Pesticides MERIAL LIMITED (US) 2009-10-20 US disclosed
US-7605134-B2 Pesticides MERIAL LIMITED (US) 2009-10-20 US disclosed
US-7538149-B2 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2009-05-26 US disclosed
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-01-29 US disclosed
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-01-29 US disclosed
US-5594003-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-14 US disclosed
US-5591762-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed
US-5459147-A Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma DR. KARL THOMAE GMBH (DE) 1995-10-17 US disclosed
EP-0346339-B1 BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION HOECHST CELANESE CORPORATION (US) 1992-09-09 EP disclosed
US-4902784-A 1,3 Disubstituted-5-diazobarbituric acids HOECHST CELANESE CORPORATION (US) 1990-02-20 US disclosed
EP-0346339-A1 BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION. HOECHST CELANESE CORP (US) 1989-12-20 EP disclosed
WO-1989005800-A1 NOVEL BARBITURIC ACID COMPOUNDS, PHOTORESISTS THEREFROM AND METHOD FOR PREPARATION HOECHST CELANESE CORPORATION (US) 1989-06-29 WO disclosed
US-4735885-A Deep UV photoresist composition with 1,3-disubstituted-5-diazobarbituric acids ALLIED CORPORATION (US) 1988-04-05 US disclosed
US-3936484-A Production of isocyanates from substituted ureas ATLANTIC RICHFIELD COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon IFNG, IFNAR1, EIF2AK2 EPHX1 1109/4885EPHX2 558/4885KDM4E 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.