Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4561038 | 0.89 | LRRK2 (0.64) | LRRK2CYP1A2 | |
| SCHEMBL4560552 | 0.89 | LRRK2 (0.51) | LRRK2CYP1A2 | |
| SCHEMBL4560277 | 0.86 | LRRK2 (0.49) | LRRK2CYP1A2 | |
| SCHEMBL5021205 | 0.83 | LRRK2 (0.59) | LRRK2CYP1A2 | |
| SCHEMBL5020932 | 0.81 | LRRK2 (0.59) | LRRK2CYP1A2 | |
| SCHEMBL10286422 | 0.80 | LRRK2 (0.61) | LRRK2CYP1A2 | |
| SCHEMBL4560266 | 0.79 | LRRK2 (0.64) | LRRK2CYP1A2 | |
| SCHEMBL19434069 | 0.79 | LRRK2 (0.44) | LRRK2 | |
| SCHEMBL4565506 | 0.79 | LRRK2 (0.63) | LRRK2CYP1A2 | |
| SCHEMBL9930260 | 0.77 | LRRK2 (0.77) | LRRK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062783-A1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-05-18 | — | — | WO | disclosed |