Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021339 | 1.00 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021337 | 1.00 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021346 | 0.93 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021338 | 0.93 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021340 | 0.93 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021324 | 0.85 | SIGMAR1 (0.42) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021318 | 0.85 | SIGMAR1 (0.42) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL5021317 | 0.85 | SIGMAR1 (0.42) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL20132497 | 0.83 | SIGMAR1 (0.52) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS | |
| SCHEMBL19840378 | 0.82 | SIGMAR1 (0.55) | SIGMAR1CHRNB2CHRNA4CHRNA7FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115893-A1 | Substituted Bicyclic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115893-A1 | Substituted Bicyclic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | TRPV1, CNR1, CNR2 | SIGMAR1 18/4885CHRNB2 536/4885CHRNA4 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.