Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370014 | 1.00 | KDM1A (0.42) | KDM1AEPAS1KMT2APOLBMEN1 | |
| SCHEMBL28983102 | 1.00 | KDM1A (0.42) | KDM1AEPAS1KMT2APOLBMEN1 | |
| SCHEMBL30370299 | 1.00 | KDM1A (0.42) | KDM1AEPAS1KMT2APOLBMEN1 | |
| SCHEMBL28983100 | 1.00 | KDM1A (0.42) | KDM1AEPAS1KMT2APOLBMEN1 | |
| SCHEMBL28983074 | 0.82 | CYP19A1 (0.47) | KMT2ACYP19A1KDM4EL3MBTL1 | |
| SCHEMBL31494783 | 0.82 | CYP19A1 (0.47) | KMT2AMEN1CYP19A1KDM4ENPC1 | |
| SCHEMBL30370012 | 0.82 | CYP19A1 (0.47) | KMT2ACYP19A1KDM4EL3MBTL1 | |
| SCHEMBL1439397 | 0.82 | SLC6A3 (0.48) | EPAS1KMT2AMEN1CYP19A1ALDH1A1 | |
| SCHEMBL30370325 | 0.82 | CYP19A1 (0.47) | KMT2AMEN1CYP19A1KDM4ENPC1 | |
| SCHEMBL28983054 | 0.82 | SLC6A3 (0.48) | EPAS1KMT2AMEN1CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |