Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021843 | 1.00 | GRM5 (0.67) | GRM5CYP2D6 | |
| SCHEMBL5022106 | 1.00 | GRM5 (0.67) | GRM5CYP2D6 | |
| SCHEMBL13642189 | 0.92 | GRM5 (0.58) | GRM5 | |
| SCHEMBL13642162 | 0.92 | GRM5 (0.58) | GRM5 | |
| SCHEMBL13642474 | 0.92 | GRM5 (0.58) | GRM5 | |
| SCHEMBL13642069 | 0.92 | GRM5 (0.58) | GRM5CYP2D6 | |
| SCHEMBL13641743 | 0.92 | GRM5 (0.58) | GRM5CYP2D6 | |
| SCHEMBL13642413 | 0.89 | GRM5 (0.71) | GRM5 | |
| SCHEMBL13642122 | 0.89 | GRM5 (0.71) | GRM5 | |
| SCHEMBL5022048 | 0.89 | GRM5 (0.54) | GRM5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283264-A1 | Oxazolidinones as Modulators of MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY | 2012-11-08 | — | — | US | disclosed |
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283264-A1 | Oxazolidinones as Modulators of MGLUR5 | GRM5, GRIK5, GRM1 | GRM5 1/4885CYP2D6 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.