Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022051 | 1.00 | GRM5 (0.50) | GRM5CYP2D6 | |
| SCHEMBL5022056 | 1.00 | GRM5 (0.50) | GRM5CYP2D6 | |
| SCHEMBL13640507 | 0.86 | GRM5 (0.68) | GRM5 | |
| SCHEMBL13640453 | 0.86 | GRM5 (0.68) | GRM5 | |
| SCHEMBL13640510 | 0.86 | GRM5 (0.68) | GRM5 | |
| SCHEMBL16364187 | 0.82 | GRM5 (0.41) | GRM5 | |
| SCHEMBL16363848 | 0.82 | GRM5 (0.41) | GRM5 | |
| SCHEMBL5022050 | 0.80 | GRM5 (0.47) | GRM5CYP2D6 | |
| SCHEMBL10279283 | 0.80 | GRM5 (0.59) | GRM5 | |
| SCHEMBL13640374 | 0.80 | GRM5 (0.59) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |